IN SEARCH OF AN O6,N7 INTERACTION OF PT(IV) WITH GUANINE - X-RAY STRUCTURE AND SOLUTION BEHAVIOR OF MER,TRANS-[(DIEN)PT(OH)2(9-MEGH-N7)](CLO4)2.2H2O

被引：22

作者：

FROMMER, G ^{[1
]}

PREUT, H ^{[1
]}

LIPPERT, B ^{[1
]}

机构：

[1] UNIV DORTMUND, FACHBEREICH CHEM, W-4600 DORTMUND, GERMANY

来源：

INORGANICA CHIMICA ACTA | 1992年 / 193卷 / 01期

关键词：

D O I：

10.1016/S0020-1693(00)83803-7

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A 9-methylguanine (9-MeGH) complex of composition mer,trans-[(dien)Pt(OH)2(9-MeGH)](ClO4)2.2H2O has been prepared and X-ray structurally and spectroscopically characterized. Pt coordination is via N7 of the guanine. The guanine O6 atom is involved in a hydrogen bond of 2.744(7) angstrom with one of the two axial OH ligands of the metal. This interaction affects the position of the v(CO) band in the IR at 1650 cm-1. The solution behaviour of the title compound is characterized by the following features: (i) reduction to [(dien)Pt(9-MeGH)]2+, (ii) mer --> fac isomerization of the dien ligand, (iii) slow substitution reaction of axial OH- by Cl-. In two instances, novel Pt(IV) 9-MeGH complexes of yet unknown composition were observed in the H-1 NMR, with guanine H8 resonances downfield (c. 8.50 ppm in D2O and MeOD) from those of the title compound. It is not clear as yet, whether they represent O6,N7 chelates.

引用

页码：111 / 117

页数：7

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