MOLECULAR AND CYTOGENETIC ANALYSES OF AUTISM IN TAIWAN

被引：38

作者：

LI, SY ^{[1
]}

CHEN, YCJ ^{[1
]}

LAI, TJ ^{[1
]}

HSU, CY ^{[1
]}

WANG, YC ^{[1
]}

机构：

[1] NATL CHENG KUNG UNIV,COLL MED,DEPT PSYCHIAT,TAINAN,TAIWAN

来源：

HUMAN GENETICS | 1993年 / 92卷 / 05期

关键词：

D O I：

10.1007/BF00216447

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Karyotypic and DNA analyses were both performed on 104 autistic children referred from Taichung Autism Education Academy and Tainan Autism Association in Taiwan. The frequency of fragile sites of the autistic patients did not differ significantly from that of the normal individuals. Of the 12 autistic children with chromosomal abnormalities, 8 had the fragile X, 2 had Down syndrome, and the remaining had other aneuploid constitutions. The results of this study illustrate the contribution of chromosomal abnormalities or variants to the pathogenesis of infantile autism.

引用

页码：441 / 445

页数：5

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