INTERPHASE AGNOR QUANTITY IS NOT RELATED TO DNA CONTENT IN 11 ESTABLISHED HUMAN CANCER CELL-LINES

被引：10

作者：

DERENZINI, M ^{[1
]}

TRERE, D ^{[1
]}

CHIECO, P ^{[1
]}

MELCHIORRI, C ^{[1
]}

机构：

[1] OSPED S ORSOLA MALPIGHI,IST ONCOL,BOLOGNA,ITALY

来源：

EXPERIMENTAL CELL RESEARCH | 1994年 / 211卷 / 02期

关键词：

D O I：

10.1006/excr.1994.1088

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The relationship between interphase AgNOR quantity and DNA ploidy was evaluated in 11 cell lines derived from human tumors of different origin. Interphase AgNOR quantity was measured by morphometric image analysis and DNA content by cytofluorometry. The mean interphase AgNOR area ranged from 5.56 to 21.12 mu m(2) and DNA ploidy from 2.05 to 3.30c. The interphase AgNOR value and DNA content were not significantly related (r = 0.23, P = 0.52). No significant correlation was found between DNA content and cell doubling time, whereas a strict relationship was confirmed to exist between interphase AgNOR quantity and rapidity of cell proliferation. (C) 1994 Academic Press,Inc.

引用

页码：282 / 285

页数：4

共 26 条

[1]

BOYUM A, 1968, SCAND J CLIN LAB INV, VS 21, P77

[2]

BROOKES CN, 1992, LAB INVEST, V67, P243

[3] CORRELATION OF NUCLEOLAR ORGANIZER REGIONS AND NUCLEAR MORPHOMETRY ASSESSED BY AUTOMATIC IMAGE-ANALYSIS IN BREAST-CANCER WITH ANEUPLOIDY, K167 IMMUNOSTAINING, HISTOPATHOLOGIC GRADE AND LYMPH-NODE INVOLVEMENT [J].

CHARPIN, C ;

BONNIER, P ;

PIANA, L ;

KOUZHAMI, H ;

DEVICTOR, B ;

LAVAUT, MN ;

ANDRAC, L ;

ALLASIA, C .

PATHOLOGY RESEARCH AND PRACTICE, 1992, 188 (08) :1009-1017

[4]

CHIECO P, 1991, CANCER, V67, P1878, DOI 10.1002/1097-0142(19910401)67:7<1878::AID-CNCR2820670711>3.0.CO

[5]

2-S

[6] CORRELATION BETWEEN DNA FLOW CYTOMETRIC AND NUCLEOLAR ORGANIZER REGION DATA IN NON-HODGKINS LYMPHOMAS [J].

CROCKER, J ;

MACARTNEY, JC ;

SMITH, PJ .

JOURNAL OF PATHOLOGY, 1988, 154 (02) :151-156

[7]

DERENZINI M, 1989, AM J PATHOL, V134, P925

[8]

DERENZINI M, 1991, VIRCHOWS ARCH B, V61, P1

[9]

DERENZINI M, 1990, LAB INVEST, V63, P137

[10]

DERENZINI M, 1991, INT REV EXP PATHOL, V32, P150

← 1 2 3 →