CYSTINE KNOTS

被引：178

作者：

ISAACS, NW

机构：

[1] Department of Chemistry, University of Glasgow, Glasgow

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1995年 / 5卷 / 03期

关键词：

D O I：

10.1016/0959-440X(95)80102-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Recent reports of the crystal structure of the glycoprotein hormone human chorionic gonadotrophin show that cystine knots are proving to be versatile structural motifs that enable the construction of a variety of proteins with different functional properties. Because of their shape, there appears to be an intrinsic requirement for the cystine-knot growth factors to form dimers. This extra level of organization increases the variety of structures built around this simple structural motif.

引用

页码：391 / 395

页数：5

共 22 条

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