CATARACTS INDUCED BY INTERMITTENT DECADRON USED AS AN ANTIEMETIC

Recent reports have shown that Decardron (dexamethasone; Merck Sharp and Dohme, West Point, Pa) has a significant antiemetic effect on cisplatin-induced vomiting. Although the development of posterior subcapsular cataracts is a known complication of systemic sterioid therapy, it usually occurs after several years of chronic administration. A young diamond dealer developed visual impairment attributed to bilateral posterior subcapsular cataracts following only four courses of intermittent Decadron used as part of a five-drug antiemetic regimen for cisplatin-associated nausea. This report is intended to alert others to the possible development of this serious complication following short-term Decadron therapy.