ETODOLAC (1,8-DIETHYL-1,3,4,9-TETRAHYDROPYRANO[3,4-B]INDOLE-1-ACETIC ACID) - A POTENT ANTIINFLAMMATORY DRUG - CONFORMATION AND ABSOLUTE-CONFIGURATION OF ITS ACTIVE ENANTIOMER

被引：42

作者：

HUMBER, LG ^{[1
]}

DEMERSON, CA ^{[1
]}

SWAMINATHAN, P ^{[1
]}

BIRD, PH ^{[1
]}

机构：

[1] CONCORDIA UNIV,MONTREAL H3G 1M8,QUEBEC,CANADA

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1986年 / 29卷 / 05期

关键词：

D O I：

10.1021/jm00155a047

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

收藏

页码：871 / 874

页数：4

相关论文

共 16 条

[1] ARNOLD J M O, 1982, Clinical Pharmacology and Therapeutics, V31, P201
[2] CONDON N, 1981, J DENT RES, V60, P562
[3] CHEMISTRY AND ANTIINFLAMMATORY ACTIVITIES OF PRODOLIC ACID AND RELATED 1,3,4,9-TETRAHYDROPYRANO[3,4-B]INDOLE-1-ALKANOIC ACIDS .1.
DEMERSON, CA
HUMBER, LG
DOBSON, TA
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1975, 18 (02) : 189 - 191
[4] RESOLUTION OF ETODOLAC AND ANTI-INFLAMMATORY AND PROSTAGLANDIN SYNTHETASE INHIBITING PROPERTIES OF THE ENANTIOMERS
DEMERSON, CA
HUMBER, LG
ABRAHAM, NA
SCHILLING, G
MARTEL, RR
PACEASCIAK, C
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1983, 26 (12) : 1778 - 1780
[5] ETODOLIC ACID AND RELATED COMPOUNDS - CHEMISTRY AND ANTIINFLAMMATORY ACTIONS OF SOME POTENT DISUBSTITUTED AND TRISUBSTITUTED 1,3,4,9-TETRAHYDROPYRANO[3,4-B]INDOLE-1-ACETIC ACIDS
DEMERSON, CA
HUMBER, LG
PHILIPP, AH
MARTEL, RR
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1976, 19 (03) : 391 - 395
[6] FRIEDRICH E, 1983, CURR THER RES CLIN E, V33, P100
[7] GABE EJ, 1979, NRC PDP8E CRYSTAL ST
[8] JACOB GB, 1983, CURR THER RES CLIN E, V33, P703
[9] ETODOLAC - EFFECT ON PROSTAGLANDIN CONCENTRATIONS IN GASTRIC-MUCOSA OF RATS
LEE, D
DVORNIK, D
[J]. LIFE SCIENCES, 1985, 36 (12) : 1157 - 1162
[10] MAIN P, 1977, MULTAN 77 SYSTEM COM