HIGHLY ENANTIOSELECTIVE ALDOL REACTION MEDIATED BY MIXED AGGREGATES DERIVED FROM A LITHIUM ESTER ENOLATE AND TETRADENTATE CHIRAL LITHIUM AMIDES

被引：27

作者：

URAGAMI, M ^{[1
]}

TOMIOKA, K ^{[1
]}

KOGA, K ^{[1
]}

机构：

[1] UNIV TOKYO,FAC PHARMACEUT SCI,BUNKYO KU,TOKYO 113,JAPAN

来源：

TETRAHEDRON-ASYMMETRY | 1995年 / 6卷 / 03期

关键词：

D O I：

10.1016/0957-4166(95)00066-X

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A highly enantioselective aldol addition reaction between a lithium ester enolate with aldehydes has been achieved in up to 96% ee for anti products by using tetradentate chiral lithium amides (2c, 2d) that are designed to form heterodimeric mixed aggregates with a lithium enolate,

引用

页码：701 / 704

页数：4

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