6-ALPHA-HYDROXY-ISO-ML-236B (6-ALPHA-HYDROXY-ISO-COMPACTIN) AND ML-236A, MICROBIAL TRANSFORMATION PRODUCTS OF ML-236B

被引：30

作者：

SERIZAWA, N ^{[1
]}

NAKAGAWA, K ^{[1
]}

TSUJITA, Y ^{[1
]}

TERAHARA, A ^{[1
]}

KUWANO, H ^{[1
]}

TANAKA, M ^{[1
]}

机构：

[1] SANKYO CO LTD,ANALYT & METAB RES LABS,SHINAGAWA KU,TOKYO 140,JAPAN

来源：

JOURNAL OF ANTIBIOTICS | 1983年 / 36卷 / 07期

关键词：

D O I：

10.7164/antibiotics.36.918

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

引用

页码：918 / 920

页数：3

共 5 条

[1] CRYSTAL AND MOLECULAR-STRUCTURE OF COMPACTIN, A NEW ANTIFUNGAL METABOLITE FROM PENICILLIUM-BREVICOMPACTUM [J].

BROWN, AG ;

SMALE, TC ;

KING, TJ ;

HASENKAMP, R ;

THOMPSON, RH .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1976, (11) :1165-1173

[2] COMPETITIVE INHIBITION OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME A REDUCTASE BY ML-236A AND ML-236B FUNGAL METABOLITES, HAVING HYPOCHOLESTEROLEMIC ACTIVITY [J].

ENDO, A ;

KURODA, M ;

TANZAWA, K .

FEBS LETTERS, 1976, 72 (02) :323-326

[3] ML-236A, ML-236B, AND ML-236C, NEW INHIBITORS OF CHOLESTEROGENESIS PRODUCED BY PENICILLIUM CITRINUM [J].

ENDO, A ;

KURODA, M ;

TSUJITA, Y .

JOURNAL OF ANTIBIOTICS, 1976, 29 (12) :1346-1348

[4] MICROBIAL HYDROXYLATION OF ML-236B (COMPACTIN) AND MONACOLIN-K (MB-530B) [J].

SERIZAWA, N ;

NAKAGAWA, K ;

HAMANO, K ;

TSUJITA, Y ;

TERAHARA, A ;

KUWANO, H .

JOURNAL OF ANTIBIOTICS, 1983, 36 (05) :604-607

[5]

SERIZAWA N, 1983, J ANTIBIOT, V36, P608

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