FEEDING OF VITAMIN-B12 RAPIDLY INCREASES THE SPECIFIC ACTIVITY OF HEPATIC METHYL-MALONYL-COA MUTASE IN VITAMIN-B12-DEFICIENT RATS

被引：6

作者：

WATANABE, F

SAIDO, H

TOYOSHIMA, S

TAMURA, Y

NAKANO, Y

机构：

[1] HAGOROMO GAKUEN COLL, NUTR & FOOD SCI LAB, 1-89-1 HAMADERO MINAMIMACHI, SAKAI, OSAKA 592, JAPAN

[2] UNIV OSAKA PREFECTURE, DEPT AGR CHEM, SAKAI, OSAKA 593, JAPAN

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 1994年 / 58卷 / 03期

关键词：

D O I：

10.1271/bbb.58.556

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Vitamin B12-deficient rats were used to study the effects of feeding vitamin B12 on hepatic methylmalonyl-CoA mutase activity, which was decreased by the deficiency. A significant and rapid increase in the specific activity of the enzyme was caused by feeding vitamin B12, suggesting that the rate of synthesis of the enzyme protein is accelerated by the feeding.

引用

页码：556 / 557

页数：2

共 13 条

[1]

BRADFORD MM, 1976, ANAL BIOCHEM, V72, P248, DOI 10.1016/0003-2697(76)90527-3

[2] CARNITINE METABOLISM IN THE VITAMIN-B-12-DEFICIENT RAT [J].