CYTOGENETIC ANALYSES OF 3 PAPILLARY CARCINOMAS AND A FOLLICULAR ADENOMA OF THE THYROID

被引:28
作者
OLAH, E
BALOGH, E
BOJAN, F
JUHASZ, F
STENSZKY, V
FARID, NR
机构
[1] DEBRECEN UNIV MED,CTR BLOOD TRANSFUS,DEPT HYG,H-4012 DEBRECEN,HUNGARY
[2] DEBRECEN UNIV MED,CTR BLOOD TRANSFUS,DEPT SURG,H-4012 DEBRECEN,HUNGARY
[3] HLTH SCI CTR,THYROID RES LAB,ST JOHNS,NEWFOUNDLAND,CANADA
关键词
D O I
10.1016/0165-4608(90)90204-N
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Cytogenetic data of three papillary carcinomas and a follicular adenoma using direct preparations or cell cultures or both after 7 to 60 days in vitro are presented. Although karyotype of the follicular adenoma proved completely normal, in each of the three papillary carcinomas a modal chromosome number in the diploid range and a deleted 11q were observed. In case 1 the del(11)(q23) was associated with rearrangement of chromosome 1 and other marker chromosomes. Our results suggest that 11q deletion may be specific for papillary carcinoma of the thyroid. © 1990.
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页码:119 / 129
页数:11
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