HRRI - A HIGH-RESOLUTION BETA- IMAGER FOR BIOLOGICAL APPLICATIONS

被引:13
作者
CHARON, Y [1 ]
BENDALI, M [1 ]
CUZON, JC [1 ]
LEBLANC, M [1 ]
MASTRIPPOLITO, R [1 ]
TRICOIRE, H [1 ]
VALENTIN, L [1 ]
机构
[1] UNIV PARIS 07,PHYS NUCL LAB,F-75221 PARIS 05,FRANCE
关键词
D O I
10.1016/0168-9002(90)91747-Y
中图分类号
TH7 [仪器、仪表];
学科分类号
0804 ; 080401 ; 081102 ;
摘要
We have developed a high-resolution β- position detector which combines a thin scintillator sheet and an intensified CCD. This device has been designed for molecular biology purposes ("in situ" hybridization). Therefore, the absolute detection efficiency, S/N ratio and spatial resolution have been studied in particular. With the first version of our detector, we achieved an intrinsic resolution of 10 μm with a relative efficiency for 35S of 99% (i.e. 18% absolute efficiency). We now present results in which another scintillator and a new triggering system have been adopted. The main result is that the absolute efficiency has been improved (up to ≈ 60% for 35S) and the background influence has been significantly reduced. These improvements can be observed on the biological image displayed in this paper. © 1990.
引用
收藏
页码:179 / 186
页数:8
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