VARIATIONS IN SEMEN PARAMETERS FROM FATHERS

被引:53
作者
COOPER, TG [1 ]
JOCKENHOVEL, F [1 ]
NIESCHLAG, E [1 ]
机构
[1] UNIV MUNSTER,INST REPROD MED,STEINFURTER STR 107,W-4400 MUNSTER,GERMANY
关键词
HUMAN SEMEN; FATHERS; SPERMATOZOA; BIOCHEMISTRY;
D O I
10.1093/oxfordjournals.humrep.a137441
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Semen volume, pH, sperm characteristics and the ejaculate content of six compounds secreted by the epididymides, prostate and seminal vesicles are presented for several semen samples from 25 men (mean age 31 years) who, without clinical assistance, had fathered children within the previous 29 months. There was a large variation both within and between individual's samples for concentrations and amounts per ejaculate of all parameters except pH. The range including 96% of all values from these fertile men are presented as standards against which samples from infertile men could be compared. Lower limits (combined arithmetic means minus twice the combined within- and between-father standard deviation) were: for semen volume, 1.9 ml; for semen pH, 7.4; for total sperm count, 39 x 10(6); for normal morphological forms, 42%; for motility (WHO grades) a, 4%; b, 19%; c, 1%; d, 19%; for curvilinear velocity, 27-mu-m/s; for total glucosidase, 27 mU/ejaculate; for neutral alpha-glucosidase, 17 mU/ejaculate; for L-carnitine, 0.4-mu-mol/ejaculate; for glycerophosphocholine, 2.4-mu-mol/ejaculate; for fructose, 15-mu-mol/ejaculate; for citrate, 30-mu-mol/ejaculate; for zinc, 2.8-mu-mol/ejaculate.
引用
收藏
页码:859 / 866
页数:8
相关论文
共 23 条
[1]  
Albertson P.C., Chang T.S.K., Vindivich D., Robinson J.C., Smyth J.W., A critical method of evaluating tests for male fertility, J. Urol, 13, pp. 467-475, (1983)
[2]  
Baker H.W.G., Clarke G.N., Sperm morphology: Consistency of assessment of the same sperm by different observers, Clin. Reprod. Fertil, 5, pp. 37-43, (1987)
[3]  
Behre H.M., Nashan D., Nieschlag E., Objective measurement of testicular volume by ultrasonography: Evaluation of the technique and comparison with orchidometer estimates, Int. J. Androl, 12, pp. 395-403, (1989)
[4]  
Cooper T.G., Yeung C.H., Nashan D., Nieschlag E., Epididymal markers in human infertility, J. Androl, 9, pp. 91-101, (1988)
[5]  
Cooper T.G., Yeung C.H., Nashan D., Jockenhovel F., Nieschlag E., Improvement in the assessment of human epididymal function by the use of inhibitors in the assay of α-glucosidase in seminal plasma, Int. J. Androl, 13, pp. 297-305, (1990)
[6]  
Cooper T.G., Weidner W., Nieschlag E., The influence of inflammation of the human male genital tract on the secretion of the seminal markers a-glucosidase, glycerophosphocholine, carnitine, fructose and citric acid, Int. J. Androl, 13, pp. 329-335, (1990)
[7]  
Freischem C.W., Knuth U.A., Langer K., Schneider H.P.G., Nieschlag E., The lack of discriminant seminal and endocrine variables in the partners of fertile and infertile women, Arch. Gynecol, 23, pp. 1-12, (1984)
[8]  
Honigl W., Knuth U.A., Nieschlag E., Selective reduction of elevated FSH levels in infertile men by pulsatile LHRH treatment, Clin. Endocrinol, 24, pp. 177-182, (1986)
[9]  
Jeyendran R.S., Van Der Ven H.H., Rosecrans R., Perez-Pelaez M., Al-Hasani S., Zaneveld L.J.D., Chemical constituents of human seminal plasma: Relationship to fertility, Andrologia, 21, pp. 423-428, (1989)
[10]  
Johnsen O., Eliasson R., Evaluation of a commercially available kit for the colorimetric determination of zinc in human semina plasma, Int. J. Androl, 10, pp. 435-440, (1987)