ECCRINE GLAND INVOLVEMENT IN KRABBES DISEASE

被引：9

作者：

ELLEDER, M

机构：

[1] First Hlava's Institute of Pathology, First Medical Faculty, Charles University, Prague 2, 12800

来源：

VIRCHOWS ARCHIV A-PATHOLOGICAL ANATOMY AND HISTOPATHOLOGY | 1992年 / 421卷 / 04期

关键词：

KRABBES DISEASE; ECCRINE GLAND STORAGE; ULTRASTRUCTURE;

D O I：

10.1007/BF01660983

中图分类号：

R602 [外科病理学、解剖学]; R32 [人体形态学];

学科分类号：

100101 ;

摘要：

Lysosomal storage inclusions were observed in skin eccrine gland secretory and myoepithelial cells in three cases of Krabbe's disease. In addition to storage there were numerous degenerative changes, occasionally resulting in cell necrosis. These findings suggest a generalized nature of the storage process in this lysosomal enzymopathy and point to high galactocerebroside turnover in eccrine gland epithelium. This knowledge may be of value in the biopsy diagnosis of Krabbe's disease.

引用

页码：351 / 354

页数：4

共 12 条

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