AERUGINOSIN-98-A AND AERUGINOSIN-98-B, TRYPSIN-INHIBITORS FROM THE BLUE-GREEN-ALGA MICROCYSTIS-AERUGINOSA (NIES-98)

被引：120

作者：

MURAKAMI, M

ISHIDA, K

OKINO, T

OKITA, Y

MATSUDA, H

YAMAGUCHI, K

机构：

[1] Laboratory of Marine Biochemistry, Faculty of Agriculture, The University of Tokyo, Bunkyo-ku, Tokyo

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 16期

关键词：

D O I：

10.1016/0040-4039(95)00396-T

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Aeruginosins 98-A and B, trypsin inhibitors, were isolated from the cultured freshwater blue-green alga Microcystis aeruginosa. Their structures were elucidated to he 1 and 2 respectively on the basis of 2D NMR data and chemical degradation. These peptides inhibited trypsin potently with an IC50 of 0.6 mu g/ml.

引用

收藏

页码：2785 / 2788

页数：4

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