DEMODICIDOSIS IN CHILDHOOD ACUTE LYMPHOBLASTIC-LEUKEMIA - AN OPPORTUNISTIC INFECTION OCCURRING WITH IMMUNOSUPPRESSION

被引：53

作者：

IVY, SP

MACKALL, CL

GORE, L

GRESS, RE

HARTLEY, A

机构：

[1] CHILDRENS NATL MED CTR, DEPT PEDIAT, HEMATOL ONCOL SECT, WASHINGTON, DC 20010 USA

[2] CHILDRENS NATL MED CTR, DEPT PEDIAT, DERMATOL SECT, WASHINGTON, DC 20010 USA

[3] GEORGE WASHINGTON UNIV, SCH MED & HLTH SCI, WASHINGTON, DC 20052 USA

[4] NCI, DIV CANC BIOL DIAG & CTR, EXPTL IMMUNOL BRANCH, BETHESDA, MD 20892 USA

来源：

JOURNAL OF PEDIATRICS | 1995年 / 127卷 / 05期

关键词：

D O I：

10.1016/S0022-3476(95)70168-0

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

We report demodicidosis in 11 children with acute lymphoblastic leukemia and a mildly pruritic, erythematous papular dermatitis that developed in areas rich in sebaceous glands. Demodex eruptions were safely and effectively treated with 5% permethrin. Proliferation of commensal parasites of the skin, Demodex folliculorum and Demodex brevis may be an opportunistic infection of the skin in the immunocompromised host; the expected abrogation of cell-mediated immunity secondary to lymphocyte depletion predisposes some children given chemotherapy for leukemia to mite proliferation.

引用

页码：751 / 754

页数：4

共 10 条

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