INVOLVEMENT OF CYTOCHROME-B-245 IN THE RESPIRATORY BURST OF HUMAN-NEUTROPHILS

被引：22

作者：

BORREGAARD, N

SIMONS, ER

CLARK, RA

机构：

[1] BOSTON UNIV, MED CTR, EVANS MEM DEPT CLIN RES, BOSTON, MA 02118 USA

[2] BOSTON UNIV, MED CTR, DEPT MED, BOSTON, MA 02118 USA

[3] BOSTON UNIV, MED CTR, DEPT BIOCHEM, BOSTON, MA 02118 USA

来源：

INFECTION AND IMMUNITY | 1982年 / 38卷 / 03期

关键词：

D O I：

10.1128/IAI.38.3.1301-1303.1982

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The cytochrome b-245 of human neutrophils was reduced when the neutrophils under anaerobic conditions were stimulated by serum-treated zymosan, immune complexes or phorbol myristate acetate. Reintroduction of O2 rapidly reoxidized the cytochrome; azide was without effect on any of these reactions. Cytochrome b-245 apparently participates in the respiratory burst of neutrophils. [The ingestion of particles by neutrophils elicits a dramatic increase in O2 consumption, known as the respiratory burst of phagocytosis.].

引用

页码：1301 / 1303

页数：3

共 15 条

[1]

BABIOR BM, 1977, BLOOD, V50, P517

[2] The extra respiration of phagocytosis [J].