EPILEPSY AND PREGNANCY - A REVIEW OF 98 PREGNANCIES

被引：25

作者：

WILHELM, J

MORRIS, D

HOTHAM, N

机构：

[1] Queen Victoria Hospital, South Australia, Rose Park

来源：

AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY | 1990年 / 30卷 / 04期

关键词：

D O I：

10.1111/j.1479-828X.1990.tb02013.x

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

This study presents the clinical and management problems in 81 epileptic patients attending the Queen Victoria Hospital for 98 pregnancies between 1985 and 1988. Epileptic women were found to have a 26.1% risk of seizure deterioration during pregnancy and the single most important factor for predicting seizure prognosis was the severity of epilepsy prepregnancy. There was a significant increase in the complications of vaginal bleeding, preeclampsia, and preterm delivery, compared with a control group of women. Infants of epileptic mothers had an increased incidence of low birth-weight and lower Apgar scores at 5 minutes. The congenital abnormality rate was 14.3% (9 major and 5 minor abnormalities). These results confirm that pregnant epileptic women are a high risk group.

引用

页码：290 / 295

页数：6

共 16 条

[1]

Macleod J., Davidson's Principles and Practice of Medicine, pp. 675-680, (1981)

[2]

Chan A., Macharper T., Lister J., Pregnancy Outcome in South Australia, (1986)

[3]

Robertson I., Epilepsy in Pregnancy, Clin Obstet Gynaecol, 13, pp. 365-381, (1986)

[4]

Hopkins A., Epilepsy and Anticonvulsant Drugs, Br Med J, 294, pp. 497-501, (1987)

[5]

Yerby MS, Problems and Management of the Pregnant Woman with Epilepsy, Epilepsia, 28, pp. 29-36, (1987)

[6]

Vihlo K., Obstetric Outcome in Women with Epilepsy, Am J Obstet Gynaecol, 152, pp. 495-504, (1985)

[7]

Buchanan N., Epilepsy and Pregnancy: a review of 26 patients, NZ Med J, 101, pp. 509-510, (1988)

[8]

Neurological Disorders of Pregnancy, pp. 65-87, (1986)

[9]

Dalessio A., Seizure Disorders and Pregnancy, N Engl J Med, 312, pp. 559-563, (1985)

[10]

Lammer EJ, Teratogen Update: Valproic Acid, Teratology, 35, pp. 465-473, (1987)

← 1 2 →