CHARACTERIZATION OF 2 NOVEL FORMS OF CHOLECYSTOKININ ISOLATED FROM BOVINE UPPER INTESTINE

被引:17
作者
CARLQUIST, M [1 ]
MUTT, V [1 ]
JORNVALL, H [1 ]
机构
[1] KAROLINSKA INST, DEPT CHEM 1, S-10401 STOCKHOLM 60, SWEDEN
关键词
D O I
10.1016/0167-0115(85)90028-X
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The primary structures of 2 novel forms of cholecystokinin, isolated from bovine upper intestine are reported. The 2 peptides are composed of 33 and 39 amino acid residues, respectively, the larger being an N-terminally extended form of the shorter peptide. The primary structure of the 39 amino acid peptide is: .**GRAPHIC**. This amino acid sequence differs from the porcine hormone at positions 13 and 15, which are Val and Met, respectively, in the pig. The same amino acid substitutions have previously been found to occur also in the dog.
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页码:27 / 34
页数:8
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