A BINARY QUINONE RECEPTOR

被引：122

作者：

HUNTER, CA ^{[1
]}

PURVIS, DH ^{[1
]}

机构：

[1] UNIV OTAGO,DEPT CHEM,DUNEDIN,NEW ZEALAND

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1992年 / 31卷 / 06期

关键词：

D O I：

10.1002/anie.199207921

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A small change produces a large effect: The replacement of two of the four isophthaloyl groups in macrocycle 1 with two pyridyl groups induces a vastly different preferred conformation for the macrocycle. Although 1 assumes an open conformation, 2 is folded. The two cavities thus formed in 2 provide binding sites for two p-benzoquinone molecules while 1 cannot bind any. The preferred conformations of 1 and 2 are shown schematically on the right.

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页码：792 / 795

页数：4

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