PHOTOPHERESIS FOR THE TREATMENT OF CUTANEOUS T-CELL LYMPHOMA

被引：62

作者：

LIM, HW

EDELSON, RL

机构：

[1] NYU, SCH MED, RONALD O PERELMAN DEPT DERMATOL, PHOTOMED SECT, NEW YORK, NY 10012 USA

[2] YALE UNIV, SCH MED, DEPT DERMATOL, NEW HAVEN, CT 06510 USA

来源：

HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA | 1995年 / 9卷 / 05期

关键词：

D O I：

10.1016/S0889-8588(18)30062-5

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Photopheresis should probably be considered to be the first line of treatment for patients with the erythrodermic stage of cutaneons T-cell lymphoma (CTCL). In responders, significant improvement of the quality of life can be achieved with minimal toxicity. Therapeutic mechanism may involve increased immunogenicity of class I-associated peptides specific for the malignant cells. Additional issues to be resolved include the role of adjunctive therapy, cost effectiveness of this treatment modality, and applicability to nonerythrodermic stages of CTCL.

引用

页码：1117 / +

页数：1

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