EXOTOXIN-A OF PSEUDOMONAS-AERUGINOSA - SUBSTITUTION OF GLUTAMIC ACID-553 WITH ASPARTIC-ACID DRASTICALLY REDUCES TOXICITY AND ENZYMATIC-ACTIVITY

被引：106

作者：

DOUGLAS, CM

COLLIER, RJ

机构：

[1] HARVARD UNIV,SCH MED,DEPT MICROBIOL & MOLEC GENET,BOSTON,MA 02115

[2] UNIV CALIF LOS ANGELES,DEPT BIOCHEM,LOS ANGELES,CA 90024

[3] SHIPLEY INST MED,BOSTON,MA 02115

来源：

JOURNAL OF BACTERIOLOGY | 1987年 / 169卷 / 11期

关键词：

D O I：

10.1128/jb.169.11.4967-4971.1987

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

引用

页码：4967 / 4971

页数：5

共 20 条

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[2] NAD BINDING-SITE OF DIPHTHERIA-TOXIN - IDENTIFICATION OF A RESIDUE WITHIN THE NICOTINAMIDE SUBSITE BY PHOTOCHEMICAL MODIFICATION WITH NAD
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[3] CARROLL SF, 1987, J BIOL CHEM, V262, P8707
[4] PHOTOAFFINITY-LABELING OF DIPHTHERIA-TOXIN FRAGMENT-A WITH NAD - STRUCTURE OF THE PHOTOPRODUCT AT POSITION-148
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[5] DAYHOFF M, 1978, ATLAS PROTEIN SEQ S3, V5, P352
[6] DEBOER HA, 1983, P NATL ACAD SCI-BIOL, V80, P21
[7] EXOTOXIN-A OF PSEUDOMONAS-AERUGINOSA - ACTIVE, CLONED TOXIN IS SECRETED INTO THE PERIPLASMIC SPACE OF ESCHERICHIA-COLI
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COLLIER, RJ
[J]. JOURNAL OF BACTERIOLOGY, 1987, 169 (11) : 4962 - 4966
[8] CLONING, NUCLEOTIDE-SEQUENCE, AND EXPRESSION IN ESCHERICHIA-COLI OF THE EXOTOXIN-A STRUCTURAL GENE OF PSEUDOMONAS-AERUGINOSA
GRAY, GL
SMITH, DH
BALDRIDGE, JS
HARKINS, RN
VASIL, ML
CHEN, EY
HEYNEKER, HL
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1984, 81 (09): : 2645 - 2649
[9] EXOTOXIN-A OF PSEUDOMONAS-AERUGINOSA - EVIDENCE THAT DOMAIN-I FUNCTIONS IN RECEPTOR-BINDING
GUIDIRONTANI, C
COLLIER, RJ
[J]. MOLECULAR MICROBIOLOGY, 1987, 1 (01) : 67 - 72
[10] FUNCTIONAL DOMAINS OF PSEUDOMONAS EXOTOXIN IDENTIFIED BY DELETION ANALYSIS OF THE GENE EXPRESSED IN ESCHERICHIA-COLI
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PASTAN, I
[J]. CELL, 1987, 48 (01) : 129 - 136

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