CLINICAL AND LABORATORY STUDIES WITH RUBELLA VACCINES IN ADULTS

被引：52

作者：

DUDGEON, JA

MARSHALL, WC

PECKHAM, CS

HAWKINS, GT

机构：

[1] the Hospital for Sick Children, London W.C.1, Great Ormond Street

[2] the Hospital for Sick Children, the Wellcome Trust, London W.C.1, Great Ormond Street

[3] Department of Virology, the Hospital for Sick Children, London W.C.1, Great Ormond Street

来源：

BRITISH MEDICAL JOURNAL | 1969年 / 1卷 / 5639期

基金：

英国惠康基金; 英国医学研究理事会;

关键词：

D O I：

10.1136/bmj.1.5639.271

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Three live attenuated rubella vaccines were tested in adult volunteers. Clinical reactions were mild, but were more noticeable in vaccinated non-immune subjects than in control subjects. With the exception of two individuals, all of the remaining 54 subjects developed an immune response; the level of antibodies found was somewhat lower than that resulting from natural infection. Though virus could be isolated from some of the seronegative volunteers after vaccination, no evidence was found of transmission of infection. © 1969, British Medical Journal Publishing Group. All rights reserved.

引用

页码：271 / &

共 20 条

[1] LIVE ATTENUATED RUBELLA VIRUS VACCINES PREPARED IN DUCK EMBRYO CELL CULTURE .I. DEVELOPMENT AND CLINICAL TESTING [J].