MIXING ECOLOGY AND EPIDEMIOLOGY

Mixing matrices can be used to describe subgroup interactions in mathematical models which have heterogeneity in population structure. A discussion is presented of two different approaches to the formulation of such mixing matrices. The relation between the two different methods is discussed, using examples based upon models of the transmission dynamics of HIV. There follows a discussion of the application of the mixing matrix approach to other areas in population biology, and a complementary overview of recent advances in theoretical ecology that may have applications in theoretical epidemiology.