Poststroke cognitive impairment and dementia: prevalence, diagnosis, and treatment

被引:32
作者
Melkas, Susanna [1 ,2 ]
Jokinen, Hanna [1 ,2 ]
Hietanen, Marja [1 ,2 ]
Erkinjuntti, Timo [1 ,2 ]
机构
[1] Helsinki Univ Cent Hosp, Dept Neurol, Helsinki, Finland
[2] Univ Helsinki, Dept Neurol Sci, Helsinki, Finland
关键词
cerebrovascular diseases; stroke; cognitive impairment; dementia;
D O I
10.2147/DNND.S37353
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Three aspects of poststroke cognitive impairment and dementia are discussed in this review: prevalence; diagnosis; and treatment. The aim is to increase awareness of poststroke cognitive impairment in order to further stimulate strategies to recognize the condition and to prevent its progression. Approximately two-thirds of all middle-aged and elderly stroke patients develop cognitive impairment, and one in three develops dementia. The standard reference for diagnosis is a detailed neuropsychological examination. Short screening tests have been used for both clinical and research purposes, but their sensitivity is limited and there is no consensus as to which test is the most appropriate. The treatment of poststroke cognitive impairment and dementia is based on effective treatment of vascular risk factors, including lifestyle - modification when needed.
引用
收藏
页码:21 / 27
页数:7
相关论文
共 60 条
[1]   Clinical presentation of the "depression-executive dysfunction syndrome" of late life [J].
Alexopoulos, GS ;
Kiosses, DN ;
Klimstra, S ;
Kalayam, B ;
Bruce, ML .
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY, 2002, 10 (01) :98-106
[2]   Prospective follow-up study between 3 and 15 months after stroke -: Improvements and decline in cognitive function among dementia-free stroke survivors > 75 years of age [J].
Ballard, C ;
Rowan, E ;
Stephens, S ;
Kalaria, R ;
Kenny, RA .
STROKE, 2003, 34 (10) :2440-2444
[3]   Previous and incident dementia as risk factors for mortality in stroke patients [J].
Barba, R ;
Morin, MDM ;
Cemillán, C ;
Delgado, C ;
Domingo, J ;
Del Ser, T .
STROKE, 2002, 33 (08) :1993-1998
[4]  
Benavente OR, 2013, LANCET, V382, P506
[5]  
Birks J, 2013, COCHRANE DB SYST REV, V4
[6]   On the emerging role of neuroimaging in determining functional and structural brain integrity induced by physical exercise: Impact for predictive, preventive, and personalized medicine [J].
Boecker H. .
EPMA Journal, 2011, 2 (3) :277-285
[7]   How predictive is the MMSE for cognitive performance after stroke? [J].
Bour, Ariane ;
Rasquin, Sascha ;
Boreas, Anita ;
Limburg, Martien ;
Verhey, Frans .
JOURNAL OF NEUROLOGY, 2010, 257 (04) :630-637
[8]  
Chollet F, 2011, LANCET NEUROL, V10, P123, DOI 10.1016/S1474-4422(10)70314-8
[9]   Diagnostic value of the Rotterdam-CAMCOG in post-stroke dementia [J].
de Koning, I ;
van Kooten, F ;
Koudstaal, PJ ;
Dippel, DWJ .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2005, 76 (02) :263-265
[10]   Prevalence of Poststroke Cognitive Impairment South London Stroke Register 1995-2010 [J].
Douiri, Abdel ;
Rudd, Anthony G. ;
Wolfe, Charles D. A. .
STROKE, 2013, 44 (01) :138-145