ELEMENTS OF A UNIQUE BACTERIORHODOPSIN NEURAL NETWORK ARCHITECTURE

被引:72
作者
HARONIAN, D
LEWIS, A
机构
[1] Hebrew University of Jerusalem, Division of Applied Physics, Jerusalem
来源
APPLIED OPTICS | 1991年 / 30卷 / 05期
关键词
D O I
10.1364/AO.30.000597
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
A rapidly reprogrammable neural network architecture with the possibility for a large synapse matrix is presented. The concept is based on the use of bacteriorhodopsin as a molecular computational element with electrooptical characteristics that are associated with a series of intermediates that are photochemically initiated. One of these states has been stabilized by several orders of magnitude with specific environmental conditions, and this allows the concentration of intermediates to be readily affected without the need for continuous holding illuminations. Thus, the photoelectrical characteristics at each synapse can readily be modulated, and a scheme has been devised to read the synaptic matrix without erasing the impressed synaptic strengths. Electrical measurements are presented to test specific aspects of the overall neural network implementation, and the results of these measurements are encouraging for the development of such a distinctive neural network device.
引用
收藏
页码:597 / 608
页数:12
相关论文
共 15 条
[1]   QUANTUM EFFICIENCY FOR PHOTOCHEMICAL CONVERSION OF PURPLE MEMBRANE-PROTEIN [J].
BECHER, B ;
EBREY, TG .
BIOPHYSICAL JOURNAL, 1977, 17 (02) :185-191
[2]  
CHEN Z, UNPUB BR ORIENTED PO
[3]  
DOWNER MC, 1984, ULTRAFAST PHONOMENA, V4
[4]   PHOTOCURRENT KINETICS OF PURPLE-MEMBRANE SHEETS BOUND TO PLANAR BILAYER-MEMBRANES [J].
FAHR, A ;
LAUGER, P ;
BAMBERG, E .
JOURNAL OF MEMBRANE BIOLOGY, 1981, 60 (01) :51-62
[5]  
GROMA GI, 1984, NATURE, V308, P577
[6]   SUBPICOSECOND SPECTROSCOPY OF BACTERIORHODOPSIN [J].
IPPEN, EP ;
SHANK, CV ;
LEWIS, A ;
MARCUS, MA .
SCIENCE, 1978, 200 (4347) :1279-1281
[7]   TIME RESOLUTION OF A BACK PHOTOREACTION IN BACTERIORHODOPSIN [J].
KALISKY, O ;
LACHISH, U ;
OTTOLENGHI, M .
PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1978, 28 (02) :261-263
[8]   DIRECT OBSERVATION OF THE FEMTOSECOND EXCITED-STATE CIS-TRANS ISOMERIZATION IN BACTERIORHODOPSIN [J].
MATHIES, RA ;
CRUZ, CHB ;
POLLARD, WT ;
SHANK, CV .
SCIENCE, 1988, 240 (4853) :777-779
[9]  
Oesterhelt D, 1974, Methods Enzymol, V31, P667
[10]  
PACKER L, 1982, METHODS ENZYMOLOGY, V88