CYTOTOXICITY OF PHENAZINE METHOSULFATE IN ISOLATED RAT HEPATOCYTES IS ASSOCIATED WITH SUPEROXIDE ANION PRODUCTION, THIOL OXIDATION AND ALTERATIONS IN INTRACELLULAR CALCIUM-ION HOMEOSTASIS

被引：17

作者：

MARIDONNEAUPARINI, I

MIRABELLI, F

RICHELMI, P

BELLOMO, G

机构：

[1] UNIV PAVIA,IST FARMACOL 2,PIAZZA BOTTA 10,I-27100 PAVIA,ITALY

[2] UNIV PAVIA,MED CLIN 1,DIPARTIMENTO MED INTERNA & TERAPIA MED,I-27100 PAVIA,ITALY

来源：

TOXICOLOGY LETTERS | 1986年 / 31卷 / 02期

关键词：

D O I：

10.1016/0378-4274(86)90012-3

中图分类号：

R99 [毒物学（毒理学）];

学科分类号：

100405 ;

摘要：

引用

页码：175 / 181

页数：7

共 22 条

[1] ALTERED THIOL AND CALCIUM HOMEOSTASIS IN OXIDATIVE HEPATOCELLULAR INJURY [J].

BELLOMO, G ;

ORRENIUS, S .

HEPATOLOGY, 1985, 5 (05) :876-882

[2] REGULATION OF INTRACELLULAR CALCIUM COMPARTMENTATION - STUDIES WITH ISOLATED HEPATOCYTES AND TERT-BUTYL HYDROPEROXIDE [J].

BELLOMO, G ;

JEWELL, SA ;

THOR, H ;

ORRENIUS, S .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1982, 79 (22) :6842-6846

[3]

BELLOMO G, 1983, MECHANISMS HEPATOCYT, P119

[4] INCREASE IN HEPATIC MIXED DISULFIDE AND GLUTATHIONE DISULFIDE LEVELS ELICITED BY PARAQUAT [J].

BRIGELIUS, R ;

LENZEN, R ;

SIES, H .

BIOCHEMICAL PHARMACOLOGY, 1982, 31 (08) :1637-1641

[5]

CAMPBELL AK, 1984, INTRACELLULAR CALCIU

[6] ALTERATIONS IN INTRACELLULAR THIOL HOMEOSTASIS DURING THE METABOLISM OF MENADIONE BY ISOLATED RAT HEPATOCYTES [J].

DIMONTE, D ;

ROSS, D ;

BELLOMO, G ;

EKLOW, L ;

ORRENIUS, S .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1984, 235 (02) :334-342

[7] BIOLOGY OF OXYGEN RADICALS [J].

FRIDOVICH, I .

SCIENCE, 1978, 201 (4359) :875-880

[8] EFFECT OF GLUCOSE AND OF POTASSIUM-IONS ON INTERCONVERSION OF 2 FORMS OF GLYCOGEN-PHOSPHORYLASE AND OF GLYCOGEN-SYNTHETASE IN ISOLATED RAT-LIVER PREPARATIONS [J].

HUE, L ;

BONTEMPS, F ;

HERS, HG .

BIOCHEMICAL JOURNAL, 1975, 152 (01) :105-114

[9]

JEWELL SA, 1986, CONTRIBUTION THIOL O

[10]

LOWRY OH, 1951, J BIOL CHEM, V193, P265

← 1 2 3 →