PATHOPHYSIOLOGY OF RENOVASCULAR HYPERTENSION

被引：170

作者：

MARTINEZMALDONADO, M ^{[1
]}

机构：

[1] UNIV IOWA, COLL MED,CTR CARDIOVASC, IOWA CITY, IA 52242 USA

来源：

HYPERTENSION | 1991年 / 17卷 / 05期

关键词：

RENOVASCULAR HYPERTENSION; RENAL HEMODYNAMICS; RENIN-ANGIOTENSIN SYSTEM; BLOOD PRESSURE REGULATION; RENAL NERVES; PROSTANOIDS; SYMPATHETIC NERVOUS SYSTEM; ANGIOTENSIN CONVERTING ENZYME INHIBITORS;

D O I：

10.1161/01.HYP.17.5.707

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Renovascular hypertension has its experimental counterpart in the two-kidney, one clip model (Goldblatt hypertension). From the study of this model, a general pathophysiological scheme has evolved suggesting that temporal stages in the development and maintenance of hypertension are regulated by complicated hormonal and neural interrelations. The central roles played by the renin-angiotensin system and the renal nerves is discussed as they relate to other hormones. In addition, the possible contribution of converting enzyme inhibitors to understanding the pathophysiology of this condition is discussed.

引用

页码：707 / 719

页数：13

共 115 条

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