HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC DETERMINATION OF GANCICLOVIR IN PLASMA

被引：25

作者：

BOULIEU, R ^{[1
]}

BLEYZAC, N ^{[1
]}

FERRY, S ^{[1
]}

机构：

[1] HOP CARDIOVASC & PNEUMOL LOUIS PRADEL,SERV PHARMACEUT,F-69394 LYONS 3,FRANCE

来源：

JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS | 1991年 / 567卷 / 02期

关键词：

CYTOMEGALO-VIRUS; INFECTIONS; DHPG;

D O I：

10.1016/0378-4347(91)80155-6

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A rapid, selective and sensitive isocratic reversed-phase high-performance liquid chromatographic method for the determination of ganciclovir in plasma samples was developed. This method, which was applied to the analysis of plasma ganciclovir from heart transplant patients under ganciclovir therapy for cytomegalovirus infections, represents a suitable analytical tool for drug monitoring and pharmacokinetic investigations.

引用

页码：480 / 484

页数：5

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