PEPTIDE HYDROLASES IN MAMMALIAN CONNECTIVE TISSUE .I. SURVEY OF ACTIVITIES AND PRELIMINARY CHARACTERIZATION OF CERTAIN PEPTIDASES

被引：14

作者：

SCHWABE, C

机构：

[1] Harvard School of Dental Medicine, Harvard Medical School, Boston

来源：

BIOCHEMISTRY | 1969年 / 8卷 / 03期

关键词：

D O I：

10.1021/bi00831a004

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A survey of the total peptide hydrolase activity of bovine fibroblasts (derived from dental pulp) allows classifications with respect to substrate specificity, chromatographic behavior, andion dependence. Identifications are by comparison with properties of known peptidases from other tissues. Approximate molecular weights of several peptide hydrolases are reported. Experiments with connective tissue slices indicate that these enzymes (in contrast to cathepsins) are probably activein this tissue at all times and that they degrade endogenous as well as exogenous peptides very readily. © 1969, American Chemical Society. All rights reserved.

引用

页码：771 / &

共 17 条

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