SYNTHETIC STUDIES ON INDOLE ALKALOIDS .3. SYNTHESIS OF 1-ETHYLINDOLO[2,3-A]QUINOLIZIDIN-2-ONE

被引：11

作者：

RUBIRALTA, M

DIEZ, A

VILA, C

机构：

[1] Laboratory of Organic Chemistry, Faculty of Pharmacy University of Barcelona

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 26期

关键词：

D O I：

10.1016/S0040-4039(00)97469-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of 1-ethylindolo[2,3-a]quinolizidin-2-one 3 is reported by potassium tert-butoxide cyclization of N-hydroxyethyl-2-[1-(phenylsulfonyl)-3-indolyl]-4-piperidone ethylene acetal 10 followed by acid treatment of the intermediate spiroindolenines 8. © 1990.

引用

页码：3779 / 3782

页数：4

共 12 条

[1] A NOVEL SYNTHESIS OF 2-ARYL-4-PIPERIDONES BY MANNICH CYCLIZATION OF IMINOKETALS
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RUBIRALTA, M
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[J]. JOURNAL OF HETEROCYCLIC CHEMISTRY, 1983, 20 (03) : 595 - 605
[2] MANNICH CYCLIZATION INVOLVING THE ALPHA-POSITION OF KETALS - SYNTHESIS OF 2-ARYL-4-PIPERIDONES AND 2-ARYL-3-ACYLPYRROLIDINES
BOSCH, J
RUBIRALTA, M
MORAL, M
[J]. HETEROCYCLES, 1982, 19 (03) : 473 - 476
[3] DIEZ A, 1990, TETRAHEDRON LETT, V31
[4] DETERMINATION OF ROTATIONAL BARRIERS OF CARBON-CARBON BONDS IN 2-ARYLPIPERIDINES
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RUBIRALTA, M
BOSCH, J
[J]. JOURNAL OF HETEROCYCLIC CHEMISTRY, 1984, 21 (03) : 715 - 720
[5] ELECTROPHILIC SUBSTITUTION IN INDOLES .3. REARRANGEMENT OF 3,3-DIALKYL INDOLENINES
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[J]. TETRAHEDRON, 1968, 24 (05) : 2227 - &
[6] NOVAK L, 1977, HETEROCYCLES, V6, P1149
[7] DETERMINATION OF ROTATIONAL BARRIERS OF C(SP2)-C(SP3) BONDS IN 2-ARYLPIPERIDINES .2. H-1-DNMR AND C-13-DNMR STUDIES OF THE TRANS-1,3-DIMETHYL-2-(3,4,5-TRIMETHOXYPHENYL)-4-PIPERIDONE
RUBIRALTA, M
FELIZ, M
JAIME, C
GIRALT, E
[J]. TETRAHEDRON, 1986, 42 (14) : 3957 - 3966
[8] RUBIRALTA M, 1990, TETRAHEDRON, V46
[9] RUBRATTA M, 1989, J ORG CHEM, V54, P5591
[10] 4-(PHENYLSULFONYL)-4H-FURO[3,4-B]INDOLE - A STABLE SYNTHETIC ANALOG OF INDOLE-2,3-QUINODIMETHANE
SAULNIER, MG
GRIBBLE, GW
[J]. TETRAHEDRON LETTERS, 1983, 24 (49) : 5435 - 5438

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