THE BIOSYNTHESIS OF THE MOLD METABOLITES ROQUEFORTINE AND ASZONALENIN FROM L-[2,4,5,6,7-H-5(2)] TRYPTOPHAN

被引：17

作者：

BHAT, B

HARRISON, DM

LAMONT, HM

机构：

[1] UNIV ULSTER,DEPT CHEM,COLERAINE BT52 1SA,NORTH IRELAND

[2] UNIV WARWICK,DEPT CHEM,COVENTRY CV4 7AL,W MIDLANDS,ENGLAND

来源：

TETRAHEDRON | 1993年 / 49卷 / 46期

关键词：

D O I：

10.1016/S0040-4020(01)81556-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

L-[2,4,5,6,7-H-2(5)]Tryptophan was incorporated into roquefortine 2 by Penicillium roqueforti and aszonalenin 3 by Aspergillus zonatus with retention in each case of five deuterium atoms; the 5a-hydrogen of both metabolites is derived from the 2-hydrogen of tryptophan.

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页码：10663 / 10668

页数：6

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