MANAGEMENT OF MULTIPLE CHOLESTEROL EMBOLIZATION SYNDROME - A CASE-REPORT

被引：22

作者：

KAWAKAMI, Y ^{[1
]}

HIROSE, K ^{[1
]}

WATANABE, Y ^{[1
]}

TOMIOKA, N ^{[1
]}

DOYAMA, K ^{[1
]}

MORIKAWA, M ^{[1
]}

KOSUGA, K ^{[1
]}

SAIGA, T ^{[1
]}

机构：

[1] OTSU RED CROSS HOSP,DEPT PATHOL,OTSU,SHIGA,JAPAN

来源：

ANGIOLOGY | 1990年 / 41卷 / 03期

关键词：

D O I：

10.1177/000331979004100311

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

A sixty-two-year-old man who underwent coronary angiography and received acute thrombolytic and anticoagulant therapy for acute myocardial infarction developed multisystemic injury, including renal insufficiency and cutaneous manifestations. Fundoscopic examination and skin biopsy specimen led to the diagnosis of multiple cholesterol embolization syndrome (MCES). Discontinuation of anticoagulants and administration of hemostatic (carbazochrome, tranexamic acid, reptilase, and vitamin K) and antihyperlipidemic (cholestyramine and probucol) drugs resulted in temporary improvement of cutaneous and renal disorders and extended survival for about one year. Besides severe aortic atherosclerosis, postmortem examination revealed numerous cholesterol emboli to multiple organs. MCES is a rare but serious complication of left heart catheterization and anticoagulant therapy, and the optimal treatment remains to be established. The authors suggest here that the above-mentioned therapy might be effective for management of MCES. © 1990, Sage Publications. All rights reserved.

引用

页码：248 / 252

页数：5

共 16 条

[1] CHOLESTEROL EMBOLISM AS A CAUSE OF TRANSIENT ISCHEMIC ATTACKS AND CEREBRAL INFARCTION [J].