BIFUNCTIONAL INTERCALATORS - RELATIONSHIP OF ANTITUMOR ACTIVITY OF DIACRIDINES TO CELL-MEMBRANE

被引：64

作者：

FICO, RM ^{[1
]}

CHEN, TK ^{[1
]}

CANELLAKIS, ES ^{[1
]}

机构：

[1] YALE UNIV,SCH MED,DEPT PHARMACOL,NEW HAVEN,CT 06510

来源：

SCIENCE | 1977年 / 198卷 / 4312期

关键词：

D O I：

10.1126/science.897680

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：53 / 56

页数：4

共 16 条

[1] DIACRIDINES - DOUBLE INTERCALATORS AS CHEMOTHERAPEUTIC-AGENTS [J].

CANELLAKIS, ES ;

FICO, RM ;

SARRIS, AH ;

SHAW, YH .

BIOCHEMICAL PHARMACOLOGY, 1976, 25 (02) :231-236

[2] DIACRIDINES - BIFUNCTIONAL INTERCALATORS .3. DEFINITION OF GENERAL SITE OF ACTION [J].

CANELLAKIS, ES ;

BONO, V ;

BELLANTONE, RA ;

KRAKOW, JS ;

FICO, RM ;

SCHULZ, RA .

BIOCHIMICA ET BIOPHYSICA ACTA, 1976, 418 (03) :300-314

[3] DIACRIDINES - BIFUNCTIONAL INTERCALATORS .2. BIOLOGICAL EFFECTS OF PUTRESCINE, SPERMIDINE AND SPERMINE DIACRIDINES ON HELA-CELLS AND ON L-1210 AND P-388 LEUKEMIA-CELLS [J].

CANELLAKIS, ES ;

BELLANTONE, RA .

BIOCHIMICA ET BIOPHYSICA ACTA, 1976, 418 (03) :290-299

[4] DIACRIDINES - BIFUNCTIONAL INTERCALATORS .1. CHEMISTRY, PHYSICAL-CHEMISTRY AND GROWTH INHIBITORY PROPERTIES [J].

CANELLAKIS, ES ;

SHAW, YH ;

HANNERS, WE ;

SCHWARTZ, RA .

BIOCHIMICA ET BIOPHYSICA ACTA, 1976, 418 (03) :277-289

[5]

CHEN TS, IN PRESS

[6]

DIMARCO A, 1975, HDB EXPT PHARMACOLOG, V38, P593

[7] DIACRIDINES, BIFUNCTIONAL INTERCALATORS .5. INHIBITION OF PROCESSING OF PRECURSOR RNA AND INHIBITION OF METHYLATION OF ESCHERICHIA-COLI TRANSFER-RNA [J].

FICO, RM ;

CANELLAKIS, ES .

BIOCHEMICAL PHARMACOLOGY, 1977, 26 (04) :275-278

[8] DIACRIDINES, BIFUNCTIONAL INTERCALATORS .4. EFFECT ON NUCLEOLAR RNA-SYNTHESIS [J].

FICO, RM ;

CANELLAKIS, ES .

BIOCHEMICAL PHARMACOLOGY, 1977, 26 (04) :269-273

[9]

Hansch C., 1971, DRUG DESIGN, V11, P271

[10]

HWANG KM, 1974, CANCER RES, V34, P3396

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