ISOHORMONAL THERAPY OF ENDOCRINE AUTOIMMUNITY

被引：63

作者：

SCHLOOT, N

EISENBARTH, GS

机构：

[1] Nanette Schloot and George S. Eisenbarth are, the Barbara Davis Center for Childhood Diabetes, University of Colorado Health Sciences Center, Denver, CO 80262

来源：

IMMUNOLOGY TODAY | 1995年 / 16卷 / 06期

关键词：

D O I：

10.1016/0167-5699(95)80183-9

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

For most autoimmune disorders, the site (if any) of chronic immunization required for perpetuation of autoimmunity is unknown. However, one possible site is the target organ itself. If this were the case, feedback regulation of target cell activity might influence autoimmunity Here, Nanette Schloot and George Eisenbarth review several recent studies suggesting that therapies that inhibit hormonal secretion of target endocrine organs, and/or modulate immunity by therapy with the isohormone, are associated with disease suppression.

引用

页码：289 / 294

页数：6

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