EFFECTIVE DETERGENT LIPID RATIOS IN THE SOLUBILIZATION OF PHOSPHATIDYLCHOLINE VESICLES BY TRITON X-100

被引：74

作者：

PARTEARROYO, MA ^{[1
]}

URBANEJA, MA ^{[1
]}

GONI, FM ^{[1
]}

机构：

[1] UNIV BASQUE COUNTRY,DEPT BIOCHEM,POB 644,E-48080 BILBAO,SPAIN

来源：

FEBS LETTERS | 1992年 / 302卷 / 02期

关键词：

SURFACTANT; DETERGENT; MEMBRANE SOLUBILIZATION; LIPOSOME; TRITON X-100;

D O I：

10.1016/0014-5793(92)80424-F

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Effective detergent:lipid ratios (i.e. molar ratios in the mixed aggregates, vesicles or micelles) have been estimated for the solubilization of phosphatidylcholine vesicles by Triton X-100. Effective molar ratios are given for both the onset and the completion of bilayer solubilization; small unilamellar, large unilamellar and multilamellar vesicles have been used. Effective detergent:lipid ratios are independent of phospholipid concentration, and their use allows a deeper understanding of membrane-surfactant interactions.

引用

页码：138 / 140

页数：3

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