ENGINEERING THERMOSTABILITY - LESSONS FROM THERMOPHILIC PROTEINS

被引：101

作者：

RUSSELL, RJM

TAYLOR, GL

机构：

[1] School of Biology and Biochemistry, University of Bath, Bath

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 1995年 / 6卷 / 04期

关键词：

D O I：

10.1016/0958-1669(95)80064-6

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

As several groups begin to tap the rich pickings found in the Archaea-a vast kingdom that stretches the concept of life as we know it-the structures of proteins from hyperthermophiles are being elucidated. Certain features are beginning to emerge, such as compactness and hydrophobic clustering, but the ability to engineer these features into temperature-intolerant proteins is still some way off.

引用

页码：370 / 374

页数：5

共 22 条

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