AN IMPROVED METHOD FOR THE DETECTION OF ALPHA(2)-ANTIPLASMIN ACTIVITY ON THE AUTOMATED COAGULATION ANALYZER MLA ELECTRA 1000C

被引：3

作者：

MEIJER, P ^{[1
]}

WESTERVELD, W ^{[1
]}

HUISMAN, LGM ^{[1
]}

机构：

[1] CTR HUMAN DRUG RES,LEIDEN,NETHERLANDS

来源：

FIBRINOLYSIS | 1994年 / 8卷

关键词：

ALPHA(2)-ANTIPLASMIN; PLASMIN; AUTOMATED METHOD;

D O I：

10.1016/0268-9499(94)90284-4

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Comparison of the results for alpha(2)-antiplasmin activity of plasma samples (n = 61, range 0-125%) obtained by the ''immediate plasmin inhibition test'' (IPIT) and by the automated method for the MLA Electra 1000C of Dade(R) shows a good correlation (R = 0.935) but a systematic disagreement especially relevant in the range below 40%. An improved method for the detection of alpha(2)-antiplasmin activity on the automated coagulation analyzer MLA Electra 1000C was developed. A linear calibration curve up to 150% was observed. A dilution curve of normal pooled plasma with plasma of an alpha(2)-antiplasmin deficient patient shows a linear curve (y = x + 7).

引用

页码：160 / 162

页数：3

共 10 条

[1]

AOKI N, 1978, CLIN CHIM ACTA, V84, P99

[2]

COLLEN D, 1978, BLOOD, V51, P563

[3] REACTIVE COAGULATION INDUCED BY PLASMIN IN PATIENTS TREATED WITH RECOMBINANT TISSUE-TYPE PLASMINOGEN-ACTIVATOR [J].