FORMULATION OF HIGHLY CONCENTRATED FLUOROCARBON EMULSIONS AND ASSESSMENT BY NEAR-TOTAL EXCHANGE PERFUSION OF THE CONSCIOUS RAT

被引：7

作者：

ARLEN, C

FOLLANA, R

LEBLANC, M

LONG, C

LONG, D

RIESS, JG

VALLA, A

机构：

[1] UNIV CALIF SAN DIEGO,SCH MED,LA JOLLA,CA 92093

[2] CTR DEPT TRANSFUS SANGUINE ALPES MARITIMES,F-06700 ST LAURENT DU VAR,FRANCE

来源：

BIOMATERIALS ARTIFICIAL CELLS AND ARTIFICIAL ORGANS | 1988年 / 16卷 / 1-3期

关键词：

Biomedical Engineering--Hemodynamics - Emulsions--Biocompatibility - Fluorohydrocarbons--Applications;

D O I：

10.3109/10731198809132599

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

100% (w/v) fluorocarbon (FC) emulsions have recently been developed as contrast agents in diagnosis. It is shown in this paper that the 50% (w/v) (ca 27% of FC by volume) emulsions derived from them by addition of salts and oncotic agents lead to high survival ratios after near-total exchange perfusion of the rat, with a safe inspired oxygen fraction (FiO2) of 0.6.

引用

页码：455 / 457

页数：3