DYSTHYMIA IN CLINICAL-PRACTICE

被引:39
作者
AKISKAL, HS
SILVA, JACE
FRANCES, A
FREEMAN, HL
KELLER, MB
LAPIERRE, YD
IBOR, JJL
PAYKEL, ES
STABL, M
机构
[1] UNIV CALIF SAN DIEGO, DEPT PSYCHIAT, LA JOLLA, CA 92093 USA
[2] WHO, DIV MENTAL HLTH, CH-1211 GENEVA, SWITZERLAND
[3] DUKE UNIV, MED CTR, DEPT PSYCHIAT, DURHAM, NC 27710 USA
[4] BROWN UNIV, DEPT PSYCHIAT & HUMAN BEHAV, PROVIDENCE, RI 02906 USA
[5] BROWN AFFILIATED HOSP, PROVIDENCE, RI 02906 USA
[6] ROYAL OTTAWA HOSP, DEPT PSYCHIAT, OTTAWA, ON K1Z 7K4, CANADA
[7] HOSP CLIN SAN CARLOS, PSYCHIAT UNIT, E-28040 MADRID, SPAIN
[8] UNIV CAMBRIDGE, ADDENBROOKES HOSP, DEPT PSYCHIAT, CAMBRIDGE CB2 2QQ, ENGLAND
[9] F HOFFMANN LA ROCHE & CO LTD, CH-4002 BASEL, SWITZERLAND
关键词
D O I
10.1192/bjp.166.2.174
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Background. Dysthymia has been reconceptualised in recent years from a personality disorder to a chronic affective disorder. It is incorporated into both the DSM and ICD diagnostic systems. Method. The members of the WPA Dysthymia Working Group combined the results of their manual literature searches with a search using Medline. Results. Available data are summarised under the headings of classification, epidemiology, validity, comorbidity, course and outcome, pharmacotherapy and psychotherapy. The coexistence of major depressive disorder, constituting 'double depression' is of particular importance. Conclusions. Improved knowledge of this disorder has led to a more positive approach to treatment, in which antidepressants can usefully be complemented by psychosocial measures. A high proportion of cases remain unrecognised in most populations, leading to prolonged morbidity and distress, much of which is now treatable.
引用
收藏
页码:174 / 183
页数:10
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