MULTISITE CLINICAL-TRIALS IN ALCOHOLISM-TREATMENT RESEARCH - ORGANIZATIONAL, METHODOLOGICAL AND MANAGEMENT ISSUES

被引：19

作者：

FULLER, RK

MATTSON, ME

ALLEN, JP

RANDALL, CL

ANTON, RF

BABOR, TF

机构：

来源：

JOURNAL OF STUDIES ON ALCOHOL | 1994年

关键词：

D O I：

10.15288/jsas.1994.s12.30

中图分类号：

R194 [卫生标准、卫生检查、医药管理];

学科分类号：

摘要：

Multisite clinical trials have two major advantages over single-site studies: the large sample size of multisite studies allows for adequate statistical power and better representativeness of the population being studied. However, they are more complex to implement than single-site studies. This article reviews previous multisite clinical trials of alcohol abuse and alcoholism, reasons for selecting a multisite design, management of such studies, and some statistical issues.

引用

页码：30 / 37

页数：8

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