PLANAR CHROMATOGRAPHY - CURRENT STATUS AND FUTURE PERSPECTIVES IN PHARMACEUTICAL ANALYSIS .1. APPLICABILITY, QUANTITATION AND VALIDATION

被引：20

作者：

SZEPESI, G

NYIREDY, S

机构：

[1] HUMAN INST SEROBACETROL RES & PROD,BUDAPEST,HUNGARY

[2] RES INST MED PLANTS,BUDAKALASZ,HUNGARY

来源：

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | 1992年 / 10卷 / 10-12期

关键词：

PLANAR CHROMATOGRAPHY; THIN-LAYER CHROMATOGRAPHY; PHARMACEUTICAL ANALYSIS; VALIDATION; QUANTITATION;

D O I：

10.1016/0731-7085(91)80112-M

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The most important features of capillary action planar chromatographic methods are summarized. Certain properties such as ease in operation, sensitivity to experimental conditions, stationary and mobile phase selection, phase system optimization, separation efficiency and detection possibilities are discussed only briefly. Other aspects such as the applicability of planar chromatographic methods in pharmaceutical analysis, quantitation and validation are considered in more detail. The advantages and limitations of different evaluation techniques (visual comparison, spot elution techniques and in situ densitometry) are also discussed. Validation steps specific to planar chromatographic methods are emphasized.

引用

页码：1007 / 1015

页数：9

共 39 条

[1] MINOR COMPONENT TABLET ANALYSIS BY HIGH-PERFORMANCE THIN-LAYER CHROMATOGRAPHY [J].

CHENG, ML ;

POOLE, CF .

JOURNAL OF CHROMATOGRAPHY, 1983, 257 (01) :140-145

[2]

Clarke E.G.C., 1969, ISOLATION IDENTIFICA, V1

[3]

CLARKE EGC, 1975, ISOLATION IDENTIFICA, V2

[4] OPTIMIZATION OF OVERPRESSURED LAYER CHROMATOGRAPHY OF POLAR, NATURALLY-OCCURRING COMPOUNDS BY THE PRISMA MODEL [J].

DALLENBACHTOELKE, K ;

NYIREDY, S ;

MEIER, B ;

STICHER, O .

JOURNAL OF CHROMATOGRAPHY, 1986, 365 :63-72

[5] COMPUTER-CONTROLLED EVALUATION IN THIN-LAYER CHROMATOGRAPHY - RESULTS AND POSSIBILITIES [J].

EBEL, S ;

HOCKE, J .

JOURNAL OF CHROMATOGRAPHY, 1976, 126 (NOV3) :449-456

[6]

EBEL S, 1979, J HIGH RES CHROMATOG, V2, P36

[7]

EBEL S, 1985, 3RD P INT S INSTR TL, P387

[8]

EBEL S, 1981, J HIGH RES CHROMATOG, V4, P337

[9]

Ebel S., 1979, J HIGH RESOL CHROMAT, V2, P133, DOI [10.1002/jhrc.1240020111, DOI 10.1002/JHRC.1240020111]

[10]

EBEL S, 1985, 3RD P INT S INSTR TL, P405

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