UROKINASE THROMBOLYTIC THERAPY OF PULMONARY-EMBOLISM IN NEUROSURGICALLY TREATED PATIENTS

被引：18

作者：

SEVERI, P ^{[1
]}

LOPINTO, G ^{[1
]}

POGGIO, R ^{[1
]}

ANDRIOLI, G ^{[1
]}

机构：

[1] GALLIERA HOSP,DEPT MED,I-16128 GENOA,ITALY

来源：

SURGICAL NEUROLOGY | 1994年 / 42卷 / 06期

关键词：

PULMONARY EMBOLISM; NEUROSURGICAL PATIENTS; THROMBOLYTIC THERAPY;

D O I：

10.1016/0090-3019(94)90074-4

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Pulmonary embolism (PE) is a severe complication in neurosurgery. The best treatment of PE is thrombolytic therapy, but the presence of either intracranial neoplasm or recent neurosurgical procedures is considered a major contraindication to this therapy. We have used urokinase thrombolytic therapy in nine of our patients with severe PE that occurred from 7 to 34 days after a neurosurgical operation. All patients survived. No intracranial hemorrhage occurred. We also advocate thrombolytic therapy for severe PE in patients who were recently operated on by neurosurgical procedure.

引用

页码：469 / 470

页数：2

共 13 条

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[2] RECOMBINANT TISSUE-TYPE PLASMINOGEN-ACTIVATOR VERSUS A NOVEL DOSING REGIMEN OF UROKINASE IN ACUTE PULMONARY-EMBOLISM - A RANDOMIZED CONTROLLED MULTICENTER TRIAL [J].