STRUCTURAL VARIATIONS ON N-ACETYLNEURAMINIC ACID .17. SYNTHESIS OF THE EPIMERIC PAIR OF 4-DEOXY-4-(R)-C-METHYL-N-ACETYLNEURAMINIC ACID AND 4-DEOXY-4-(S)-C-METHYL-N-ACETYLNEURAMINIC ACID

被引：16

作者：

HARTMANN, M ^{[1
]}

ZBIRAL, E ^{[1
]}

机构：

[1] UNIV VIENNA, INST ORGAN CHEM, WAHRINGERSTR 38, A-1090 VIENNA, AUSTRIA

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 20期

关键词：

D O I：

10.1016/0040-4039(90)80171-H

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A 4-C-methylene sialic acid derivative 3 was obtained by the reaction of the corresponding 4-oxocompound 2 with CH2I/Zn/CP2ZrCl2. The product was transformed into a mixture of the 4-deoxy-4-(R)-methyl- and 4-(S)-methyl derivatives 4 and 5. Sialic acids 6 and 7 were obtained after the removal of protective groups. © 1990.

引用

页码：2875 / 2878

页数：4

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