HUMAN AND MURINE CYTOSOLIC EPOXIDE HYDROLASE - PHYSICAL AND STRUCTURAL-PROPERTIES

被引：18

作者：

DIETZE, EC

MAGDALOU, J

HAMMOCK, BD

机构：

[1] UNIV CALIF DAVIS,DEPT ENTOMOL,DAVIS,CA 95616

[2] UNIV CALIF DAVIS,DEPT ENVIRONM TOXICOL,DAVIS,CA 95616

来源：

INTERNATIONAL JOURNAL OF BIOCHEMISTRY | 1990年 / 22卷 / 05期

关键词：

D O I：

10.1016/0020-711X(90)90258-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. 1. Human and murine liver cytosolic epoxide hydrolase (CEH) had an apparent Mw of 59,000 by SDS-PAGE. 2. 2. Peptide maps of CNBr, trypsin and Slaphylococcus aureus V8 digests, as well as amino acid analysis, showed that human and murine CEH were similar. Uninduced and clofibrate induced murine CEH appeared qualitatively identical. 3. 3. The CEHs shared antigenic determinants as determined by Western blotting. 4. 4. Circular dichroism spectra indicate that human CEH had 39% α-helix. Uninduced and clofibrate induced murine CEH had 38 and 35% α-helix, respectively. © 1990.

引用

页码：461 / 470

页数：10

共 45 条

[1] ISOLATION AND CHARACTERIZATION OF NATURAL ALLENE OXIDES - UNSTABLE INTERMEDIATES IN THE METABOLISM OF LIPID HYDROPEROXIDES
BRASH, AR
BAERTSCHI, SW
INGRAM, CD
HARRIS, TM
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (10) : 3382 - 3386
[2] VASOACTIVITY OF ARACHIDONIC-ACID EPOXIDES
CARROLL, MA
SCHWARTZMAN, M
CAPDEVILA, J
FALCK, JR
MCGIFF, JC
[J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 1987, 138 (02) : 281 - 283
[3] EPOXY DERIVATIVES OF ARACHIDONIC-ACID ARE POTENT STIMULATORS OF PROLACTIN SECRETION
CASHMAN, JR
HANKS, D
WEINER, RI
[J]. NEUROENDOCRINOLOGY, 1987, 46 (03) : 246 - 251
[4] DETERMINATION OF SECONDARY STRUCTURES OF PROTEINS BY CIRCULAR-DICHROISM AND OPTICAL ROTATORY DISPERSION
CHEN, YH
YANG, JT
MARTINEZ, HM
[J]. BIOCHEMISTRY, 1972, 11 (22) : 4120 - +
[5] ASSESSMENT OF PROTEIN SEQUENCE IDENTITY FROM AMINO-ACID COMPOSITION DATA
CORNISHBOWDEN, A
[J]. JOURNAL OF THEORETICAL BIOLOGY, 1977, 65 (04) : 735 - 742
[6] DUBOIS GC, 1978, J BIOL CHEM, V253, P2932
[7] THE EFFECT OF HEPATIC-MICROSOMAL AND CYTOSOLIC SUBCELLULAR-FRACTIONS ON THE MUTAGENIC ACTIVITY OF EPOXIDE-CONTAINING COMPOUNDS IN THE SALMONELLA ASSAY
ELTANTAWY, MA
HAMMOCK, BD
[J]. MUTATION RESEARCH, 1980, 79 (01): : 59 - 71
[8] FITZPATRICK FA, 1986, J BIOL CHEM, V261, P5334
[9] MOLECULAR-CLONING AND AMINO-ACID-SEQUENCE OF LEUKOTRIENE-A4 HYDROLASE
FUNK, CD
RADMARK, O
FU, JY
MATSUMOTO, T
JORNVALL, H
SHIMIZU, T
SAMUELSSON, B
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (19) : 6677 - 6681
[10] MICROSOMAL AND CYTOSOLIC EPOXIDE HYDROLASES IN RHESUS-MONKEY LIVER, AND IN NORMAL AND NEOPLASTIC HUMAN-LIVER
GILL, SS
OTA, K
RUEBNER, B
HAMMOCK, BD
[J]. LIFE SCIENCES, 1983, 32 (23) : 2693 - 2700

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