EFFECTS OF AN AQUEOUS EXTRACT OF FERULA-OVINA ON RABBIT AND GUINEA-PIG SMOOTH-MUSCLE

被引：16

作者：

ALKHALIL, S

AQEL, M

AFIFI, F

ALEISAWI, D

机构：

[1] UNIV JORDAN,FAC SCI,AMMAN,JORDAN

[2] UNIV JORDAN,FAC MED,AMMAN,JORDAN

[3] UNIV JORDAN,FAC PHARM,AMMAN,JORDAN

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 1990年 / 30卷 / 01期

关键词：

D O I：

10.1016/0378-8741(90)90015-L

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The effects of an aqueous extract of Ferula ovina were tested in vitro using isolated segments of rabbit and guinea pig intestine, trachea and aorta. The extract inhibited the spontaneous movements of rabbit jejunum and guinea pig ileum and the contractions induced by acetylcholine. The aqueous extract also inhibited the contractions of rabbit trachealis muscle induced by acetylcholine and the contractions of guinea pig trachealis muscle induced by histamine. These inhibitions were dose-dependent and reversible. However, the aqueous extract did not inhibit the contractions of rabbit and guinea pig aortic rings induced by norepinephrine. These data suggest that this plant has non-specific anticholinergic and antihistaminic antispasmodic effects. © 1990.

引用

页码：35 / 42

页数：8

共 19 条

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ASHRAF M, 1980, Pakistan Journal of Scientific and Industrial Research, V23, P68

[2]

BABAEV NF, 1983, AZERBAIDZHANSKII MED, V60, P67

[3] MECHANISMS OF ACTION OF TRANSMITTERS AND OTHER SUBSTANCES ON SMOOTH-MUSCLE [J].