RHEUMATOID-ARTHRITIS IN THE AGED - INCIDENCE AND OPTIMAL MANAGEMENT

被引:16
作者
NESHER, G
MOORE, TL
机构
[1] ST LOUIS UNIV,SCH MED,DIV RHEUMATOL,1402 S GRAND BLVD,ST LOUIS,MO 63104
[2] SHAARE ZEDEK MED CTR,IL-91000 JERUSALEM,ISRAEL
关键词
D O I
10.2165/00002512-199303060-00003
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Rheumatoid arthritis (RA) is estimated to occur in 0.3 to 3% of the general population. Up to one-third of RA patients first present for treatment after the age of 60 years (elderly-onset RA). The overall frequency in individuals older than 65 is increased so that 30 to 40% of RA patients treated in rheumatology centres are > 60 years of age. Optimal management of all RA patients includes physical therapy, medications, both nonsteroidal anti-inflammatory drugs (NSAIDs) and remittive agents, and, in some cases, surgery. In the elderly, these treatment modalities at times need to be altered to accommodate age-related changes in body mechanics and organ function. Thus, the approach to physical therapy in older patients is different than in the young. There are fewer rest periods and more passive exercises. Drug treatment must also be modified, since NSAIDs and several remittive agents are more hazardous in elderly patients. Indications for orthopaedic procedures may also be different. The long term management of RA requires a delicate balance of benefit and risk. It is wise to begin with the least toxic medications. However, if necessary, potentially toxic medications can be given cautiously, with close monitoring for adverse effects.
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页码:487 / 501
页数:15
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