MANAGEMENT OF PITUITARY-GONADAL FUNCTION VIA GONADOTROPIN-RELEASING-HORMONE (GNRH) ANTAGONISTS, INCLUDING OVULATION INDUCTION BY COADMINISTRATION OF EITHER GONADOTROPINS OR PULSATILE GNRH

被引：1

作者：

GORDON, K

IRIANNI, F

HODGEN, GD

机构：

[1] The Jones Institute for Reproductive Medicine, Eastern Virginia Medical School, Department of Obstetrics and Gynecology, Norfolk, VA, 23507

来源：

HUMAN REPRODUCTION | 1993年 / 8卷

基金：

美国安德鲁·梅隆基金会;

关键词：

GNRH ANTAGONISTS; GONADOTROPINS; OVULATION INDUCTION; PULSATILE GNRH;

D O I：

10.1093/humrep/8.suppl_2.204

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

GnRH agonists are now familiar clinical agents and are often the drugs of choice for suppression of the pituitary gonadal axis as part of various clinical indications. GnRH antagonists, which are likely to become clinically available soon, offer several advantages over the currently available GnRH agonists for many applications including ovulation induction. Here, we review the results from a series of pre-clinical studies designed to evaluate the potential clinical utility of this new class of compounds for ovulation induction

引用

页码：204 / 209

页数：6

共 45 条

[1]

ADASHI EY, 1990, FERTIL STERIL, V53, P765

[2] TREATMENT OF HIRSUTISM WITH A GONADOTROPIN-RELEASING-HORMONE AGONIST (NAFARELIN) [J].

ANDREYKO, JL ;

MONROE, SE ;

JAFFE, RB .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1986, 63 (04) :854-859

[3]

ASHKENAZI J, 1989, HUM REPROD, V6, P667

[4] THE POLYCYSTIC OVARY SYNDROME - PATHOGENESIS AND TREATMENT [J].

BARNES, R ;

ROSENFIELD, RL .

ANNALS OF INTERNAL MEDICINE, 1989, 110 (05) :386-399

[5]

BYRD S, 1992, FERTIL STERIL, V57, P209

[6] DYNAMICS OF PLASMA GONADOTROPIN AND SEX STEROID RELEASE IN POLYCYSTIC OVARIAN DISEASE AFTER PITUITARY-OVARIAN INHIBITION WITH AN ANALOG OF GONADOTROPIN-RELEASING-HORMONE [J].

CALOGERO, AE ;

MACCHI, M ;

MONTANINI, V ;

MONGIOI, A ;

MAUGERI, G ;

VICARI, E ;

CONIGLIONE, F ;

SIPIONE, C ;

DAGATA, R .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1987, 64 (05) :980-985

[7]

CASPI E, 1989, FERTIL STERIL, V51, P95

[8] COMPARISON OF INTERMITTENT AND CONTINUOUS USE OF A GONADOTROPIN-RELEASING-HORMONE ANTAGONIST (NAL-GLU) IN INVITRO FERTILIZATION CYCLES - A PRELIMINARY-REPORT [J].

CASSIDENTI, DL ;

SAUER, MV ;

PAULSON, RJ ;

DITKOFF, EC ;

RIVIER, J ;

YEN, SSC ;

LOBO, RA .

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1991, 165 (06) :1806-1810

[9] STEROID-SECRETION IN POLYCYSTIC OVARIAN DISEASE AFTER OVARIAN SUPPRESSION BY A LONG-ACTING GONADOTROPIN-RELEASING HORMONE AGONIST [J].

CHANG, RJ ;

LAUFER, LR ;

MELDRUM, DR ;

DEFAZIO, J ;

LU, JKH ;

VALE, WW ;

RIVIER, JE ;

JUDD, HL .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1983, 56 (05) :897-903

[10]

CHESKOWSKI RJ, 1989, FERTIL STERIL, V52, P250

← 1 2 3 4 5 →