QUANTITATIVE MAGNETIC-RESONANCE-IMAGING OF THE LUMBAR SPINE - POTENTIAL FOR INVESTIGATIONS OF WATER-CONTENT AND BIOCHEMICAL-COMPOSITION

被引：24

作者：

BOOS, N

BOESCH, C

机构：

[1] UNIV BERN,INSELSPITAL,DEPT ORTHOPAED SURG,CH-3010 BERN,SWITZERLAND

[2] UNIV BERN,DEPT MR SPECT & METHODOL,BERN,SWITZERLAND

来源：

SPINE | 1995年 / 20卷 / 21期

关键词：

BIOCHEMISTRY; INTERVERTEBRAL DISC; LUMBAR SPINE; METHODOLOGY; PROTON DENSITY; QUANTITATIVE MAGNETIC RESONANCE IMAGING; RELAXATION TIMES;

D O I：

10.1097/00007632-199511000-00018

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Ouantitative magnetic resonance imaging (relaxation time and proton density measurements) has gained increasing interest as a noninvasive way to study changes in water content and biochemical composition of lumbar intervertebral discs and vertebral bodies. This article reviews the current methodological problems and the feasibility of quantitative magnetic resonance imaging in the lumbar spine for investigations on water content and biological composition. This technique does not allow direct quantification of water content. Although biochemical variations may sensitively influence relaxation times and proton density under in vitro conditions, it is not feasible to obtain sufficiently reliable and specific information to monitor biochemical alterations associated with lumbar disc pathology in vivo.

引用

页码：2358 / 2365

页数：8

共 83 条

[1]

Basser P., Mattiello J., Lebihan D., MR diffusion tensor spectroscopy and imaging, Biophys J, 66, pp. 259-267, (1994)

[2]

Beall P.T., Amtey S.R., Kasturi S.R., Measurement of Relaxation Times. In: NMR Data Handbook for Biomedical Applications, pp. 32-39, (1984)

[3]

Beall P.T., Amtey S.R., Kasturi S.R., Practical Methods for Biological NMR Sample Handling. In: NMR Data Handbook for Biomedical Applications, pp. 40-55, (1984)

[4]

Beall P.T., Hazlewood C.F., Rao P.N., Nuclear magnetic resonance patterns of intracellular water as a function of HeLa cell cycle, Science, 192, pp. 904-907, (1976)

[5]

Bellon E.M., Haacke E.M., Coleman P.E., Sacco D.C., Steiger D.A., Gangarosa R.E., MR artifacts: A review, AJR am J Roentgenol, 147, pp. 1271-1281, (1986)

[6]

Boos N., Wallin A., Gbedegbegnon T., Aebi M., Boesch C., Quantitative MR imaging of lumbar intervertebral disks and vertebral bodies: Influences of diurnal water content variations, Radiology, 188, pp. 351-354, (1993)

[7]

Boos N., Wallin A., Schmucker T., Aebi M., Boesch Ch. Quantitative MR imaging of lumbar intervertebral discs and vertebral bodies: Methodology, reproducibility and preliminary results, Magn Reson Imaging, 12, pp. 577-587, (1994)

[8]

Bottomley P.A., Foster T.H., Argensinger R.E., Pfeifer L.M., A review of normal tissue hydrogen NMR relaxation times and relaxation mechanisms from 1-100MHz: Dependence on tissue type, NMR frequency, temperature, species, excision, and age, Med Phys, 11, pp. 425-448, (1984)

[9]

Bottomley P.A., Hardy C.J., Argersinger R.E., Allen-More G., A review of Hnuclear magnetic resonance relaxation in pathology: Are T l and T2diagnostic, Med Phys, 14, (1987)

[10]

Bradley W.G., Flow phenomena, Magnetic Resonance Imaging, pp. 253-298, (1992)

← 1 2 3 4 5 6 7 8 9 →