TRANSFORMATION OF C-TERMINAL SERINE AND THREONINE EXTENDED PRECURSORS INTO C-TERMINAL ALPHA-AMIDATED PEPTIDES - A POSSIBLE CHEMICAL-MODEL FOR THE ALPHA-AMIDATING ACTION OF PITUITARY ENZYMES

被引：29

作者：

RANGANATHAN, D

SAINI, S

机构：

[1] Department of Chemistry, Indian Institute of Technology

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1991年 / 113卷 / 03期

关键词：

D O I：

10.1021/ja00003a048

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

[No abstract available]

引用

页码：1042 / 1044

页数：3

共 18 条

[1]

BATEMAN RC, 1985, J BIOL CHEM, V260, P9088

[2] ENZYME-CATALYZED PEPTIDE AMIDATION - ISOLATION OF A STABLE INTERMEDIATE FORMED BY REACTION OF THE AMIDATING ENZYME WITH AN IMINO ACID [J].

BRADBURY, AF ;

SMYTH, DG .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1987, 169 (03) :579-584

[3] MECHANISM OF C-TERMINAL AMIDE FORMATION BY PITUITARY ENZYMES [J].

BRADBURY, AF ;

FINNIE, MDA ;

SMYTH, DG .

NATURE, 1982, 298 (5875) :686-688

[4] BIOSYNTHESIS OF THE C-TERMINAL AMIDE IN PEPTIDE-HORMONES [J].

BRADBURY, AF ;

SMYTH, DG .

BIOSCIENCE REPORTS, 1987, 7 (12) :907-916

[5] PEPTIDE ALPHA-AMIDATION [J].

EIPPER, BA ;

MAINS, RE .

ANNUAL REVIEW OF PHYSIOLOGY, 1988, 50 :333-344

[6] IDENTIFICATION IN PITUITARY TISSUE OF A PEPTIDE ALPHA-AMIDATION ACTIVITY THAT ACTS ON GLYCINE-EXTENDED PEPTIDES AND REQUIRES MOLECULAR-OXYGEN, COPPER, AND ASCORBIC-ACID [J].

EIPPER, BA ;

MAINS, RE ;

GLEMBOTSKI, CC .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (16) :5144-5148

[7]

FONTANA A, 1986, PRACTICAL PROTEIN CH

[8] SELECTIVE CHEMICAL CLEAVAGE OF THREONINE PEPTIDES [J].

KANEKO, T ;

KUSUMOTO, S ;

INUI, T ;

SHIBA, T .

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1968, 41 (09) :2155-+

[9] SELECTIVE CLEAVAGE OF SERINE PEPTIDES [J].

KANEKO, T ;

TAKEUCHI, I ;

INUI, T .

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1968, 41 (04) :974-+

[10] NOVEL SUBSTRATES AND INHIBITORS OF PEPTIDYLGLYCINE ALPHA-AMIDATING MONOOXYGENASE [J].

KATOPODIS, AG ;

MAY, SW .

BIOCHEMISTRY, 1990, 29 (19) :4541-4548

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