RESECTION OF THE INFERIOR VENA-CAVA OR INTRALUMINAL VENA-CAVAL TUMOR THROMBECTOMY DURING RETROPERITONEAL LYMPH-NODE DISSECTION FOR METASTATIC GERM-CELL CANCER - INDICATIONS AND RESULTS

被引:34
作者
DONOHUE, JP
THORNHILL, JA
FOSTER, RS
ROWLAND, RG
BIHRLE, R
机构
[1] Department of Urology, Indiana University Med. Center, Indianapolis, IN
关键词
VENA CAVA; INFERIOR; CARCINOMA; TESTIS; THROMBOSIS; LYMPH NODE EXCISION;
D O I
10.1016/S0022-5347(17)37789-3
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
A total of 42 patients underwent inferior vena caval resection (40) or intraluminal tumor thrombectomy (2) during retroperitoneal lymph node dissection for bulky abdominal metastatic nonseminomatous germ cell cancer (7% of all post-chemotherapy retroperitoneal lymph node dissection cases). The 3 indications for vena caval resection included tumor clearance (38%), vena caval scar occlusion (14%) and vena caval tumor thrombus (48%). En bloc vena caval resection to achieve tumor clearance was justified by subsequent nodal pathology (cancer is 63% of the specimens and teratoma in 31%). Vena caval resection in the presence of scar occlusion was de facto required by virtue of its incorporation in the specimen. Vena caval resection or thrombectomy is indicated for intraluminal tumor thrombus because thrombus pathology (cancer 35%, teratoma 45% and fibrosis 20%) reflected nodal pathology in 71% of the patients with cancer, 78% with teratoma and 100% with fibrosis. The complications of vena caval resection were generally transitory. The 71% survival rate justifies this intensive surgical approach because these patients had exhausted all chemotherapy options.
引用
收藏
页码:346 / 349
页数:4
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